Phylum Sarcomastigophora; Class Zoomastigophora -- What is sleepingsickness?

Phylumsarcomastigophora

Class Zoomastigophora

Trypanosoma brucei (a species of Trypanosoma):

Sub species of trypanosoma brucei: T.b. brucei, T.b. gambiense, T.b. rhodesiense.
collectively known as a Trypanosoma brucei complex.
The first she is a parasite of nonhuman mammals of Africa. The latter two cause sleeping sickness in humans.
Vector of Trypanosoma brucei: Tsetse fly (Glossina spp.) Is an intermediate host and vector of all three subspecies.

Disease cycle

Cycle in the fly:

A tsetse fly bites an infected human or mammal,
Sucks blood and picks up parasites,
trypanosomes multiply asexually in the gut of the fly for about 10 days, migrate to the salivary glands,
forms a number of body forms in 15 to 35 days.

Cycle in vertebrate host:

Infected tsetse fly bites another vertebrate host
The parasite travel with salivary secretions into the blood of a new definitive host
The parasites multiply asexually in the new host
It again transforms through a number of body forms

Disease cycle:

The parasite lives in blood lymph, spleen, central nervous system, and cerebrospinal fluid.
Diseases caused: apathy, mental dullness, and lack of coordination. Sleepiness develops in a host.
An infected individual may fall asleep during normal day time activities
It may cause death due to previous symptoms of heart failure, malnutrition, and other weakened conditions.
Sleeping sickness is curable at the early stages. But recovery is impossible in advanced infection of the central nervous system.